Protecting the brain from infection may start with a gut reaction

Some immune defenses of the brain may have their roots in the gut.

A new study in mice finds that immune cells are first trained in the gut to recognize and launch attacks on pathogens, and then migrate to the brain’s surface to protect it, researchers report online November 4 in Nature. These cells were also found in surgically removed parts of human brains.

Every minute, around 750 milliliters of blood flow through the brain, giving bacteria, viruses or other blood-borne pathogens an opportunity to infect the organ. For the most part, the invaders are kept out by three membrane layers, called the meninges, which wrap around the brain and spinal cord and act as a physical barrier. If a pathogen does manage to breach that barrier, the researchers say, the immune cells trained in the gut are ready to attack by producing a battalion of antibodies.

The most common route for a pathogen to end up in the bloodstream is from the gut. “So, it makes perfect sense for these [immune cells] to be educated, trained and selected to recognize things that are present in the gut,” says Menna Clatworthy, an immunologist at the University of Cambridge.

Clatworthy’s team found antibody-producing plasma cells in the leathery meninges, which lie between the brain and skull, in both mice and humans. These immune cells produced a class of antibodies called immunoglobulin A, or IgA.

These cells and antibodies are mainly found in the inner lining of the gut and lungs, so the scientists wondered if the cells on the brain had any link to the gut. It turned out that there was: Germ-free mice, which had no microbes in their guts, didn’t have any plasma cells in their meninges either. However, when bacteria from the poop of other mice and humans were transplanted into the mice’s intestines, their gut microbiomes were restored, and the plasma cells then appeared in the meninges.

“This was a powerful demonstration of how important the gut could be at determining what is found in the meninges,” Clatworthy says.

Researchers captured microscope images of an attack in the meninges of mice that was led by plasma cells that had likely been trained in the guts. When the team implanted a pathogenic fungus, commonly found in the intestine, into the mice’s bloodstream, the fungus attempted to enter the brain through the walls of blood vessels in the meninges. However, plasma cells in the membranes formed a mesh made of IgA antibodies around the pathogen, blocking its entry. The plasma cells are found along the blood vessels, Clatworthy says, where they can quickly launch an attack on pathogens.

“To my knowledge, this is the first time anyone has shown the presence of plasma cells in the meninges. The study has rewritten the paradigm of what we know about these plasma cells and how they play a critical role in keeping our brain healthy,” says Matthew Hepworth, an immunologist at the University of Manchester in England who was not involved with the study. More research is needed to classify how many of the plasma cells in the meninges come from the gut, he says.

The finding adds to growing evidence that gut microbes can play a role in brain diseases. A previous study, for instance, suggested that in mice, boosting a specific gut bacterium could help fight amyotrophic lateral sclerosis, or ALS, a fatal neurological disease that results in paralysis (SN: 7/22/19). And while the new study found the plasma cells in the brains of healthy mice, previous research has found other gut-trained cells in the brains of mice with multiple sclerosis, an autoimmune disease of the brain and the spinal cord.

For now, the researchers want to understand what cues plasma cells follow in the guts to know it is time for them to embark on a journey to the brain.

With Theta, 2020 sets the record for most named Atlantic storms

It’s official: 2020 now has the most named storms ever recorded in the Atlantic in a single year.

On November 9, a tropical disturbance brewing in the northeastern Atlantic Ocean gained enough strength to become a subtropical storm. With that, Theta became the year’s 29th named storm, topping the 28 that formed in 2005.

With maximum sustained winds near 110 kilometers per hour as of November 10, Theta is expected to churn over the open ocean for several days. It’s too early to predict Theta’s ultimate strength and trajectory, but forecasters with the National Oceanic and Atmospheric Administration say they expect the storm to weaken later in the week.

If so, like most of the storms this year, Theta likely won’t become a major hurricane. That track record might be the most surprising thing about this season — there’s been a record-breaking number of storms, but overall they’ve been relatively weak. Only five — Laura, Teddy, Delta, Epsilon and Eta — have become major hurricanes with winds topping 178 kilometers per hour, although only Laura and Eta made landfall near the peak of their strength as Category 4 storms.

Even so, the 2020 hurricane season started fast, with the first nine storms arriving earlier than ever before (SN: 9/7/20). And the season has turned out to be the most active since naming began in 1953, thanks to warmer-than-usual water in the Atlantic and the arrival of La Niña, a regularly-occurring period of cooling in the Pacific, which affects winds in the Atlantic and helps hurricanes form (SN: 9/21/19). If a swirling storm reaches wind speeds of 63 kilometers per hour, it gets a name from a list of 21 predetermined names. When that list runs out, the storm gets a Greek letter.

While the wind patterns and warm Atlantic water temperatures set the stage for the string of storms, it’s unclear if climate change is playing a role in the number of storms. As the climate warms, though, you would expect to see more of the destructive, high-category storms, says Kerry Emanuel, an atmospheric scientist at MIT. “And this year is not a poster child for that.” So far, no storm in 2020 has been stronger than a Category 4. The 2005 season had multiple Category 5 storms, including Hurricane Katrina (SN: 12/20/05).

There’s a lot amount of energy in the ocean and atmosphere this year, including the unusually warm water, says Emanuel. “The fuel supply could make a much stronger storm than we’ve seen,” says Emanuel, “so the question is: What prevents a lot of storms from living up to their potential?”
A major factor is wind shear, a change in the speed or direction of wind at different altitudes. Wind shear “doesn’t seem to have stopped a lot of storms from forming this year,” Emanuel says, “but it inhibits them from getting too intense.” Hurricanes can also create their own wind shear, so when multiple hurricanes form in close proximity, they can weaken each other, Emanuel says. And at times this year, several storms did occupy the Atlantic simultaneously — on September 14, five storms swirled at once.

It’s not clear if seeing hurricane season run into the Greek alphabet is a “new normal,” says Emanuel. The historical record, especially before the 1950s is spotty, he says, so it’s hard to put this year’s record-setting season into context. It’s possible that there were just as many storms before naming began in the ‘50s, but that only the big, destructive ones were recorded or noticed. Now, of course, forecasters have the technology to detect all of them, “so I wouldn’t get too bent out of shape about this season,” Emanuel says.

Some experts are hesitant to even use the term “new normal.”

“People talk about the ‘new normal,’ and I don’t think that is a good phrase,” says James Done, an atmospheric scientist at the National Center for Atmospheric Research in Boulder, Colo. “It implies some new stable state. We’re certainly not in a stable state — things are always changing.”

Climate change may be shrinking tropical birds

In a remote corner of Brazil’s Amazon rainforest, researchers have spent decades catching and measuring birds in a large swath of forest unmarred by roads or deforestation. An exemplar of the Amazon’s dazzling diversity, the experimental plot was to act as a baseline that would reveal how habitat fragmentation, from logging or roads, can hollow out rainforests’ wild menagerie.

But in this pristine pocket of wilderness, a more subtle shift is happening: The birds are shrinking.

Over 40 years, dozens of Amazonian bird species have declined in mass. Many species have lost nearly 2 percent of their average body weight each decade, researchers report November 12 in Science Advances. What’s more, some species have grown longer wings. The changes coincide with a hotter, more variable climate, which could put a premium on leaner, more efficient bodies that help birds stay cool, the researchers say.

“Climate change isn’t something of the future. It’s happening now and has been happening and has effects we haven’t thought of,” says Ben Winger, an ornithologist at the University of Michigan in Ann Arbor who wasn’t involved in the research but has documented similar shrinkage in migratory birds. Seeing the same patterns in so many bird species across widely different contexts “speaks to a more universal phenomenon,” he says.

Biologists have long linked body size and temperature. In colder climates, it pays to be big because having a smaller surface area relative to one’s volume reduces heat loss through the skin and keeps the body warmer. As the climate warms, “you’d expect shrinking body sizes to help organisms off-load heat better,” says Vitek Jirinec, an ecologist at the Integral Ecology Research Center in Blue Lake, Calif.

Many species of North American migratory birds are getting smaller, Winger and colleagues reported in 2020 in Ecology Letters. Climate change is the likely culprit, Winger says, but since migrators experience a wide range of conditions while globe-trotting, other factors such as degraded habitats that birds may encounter can’t be ruled out.

To see if birds that stay put have also been shrinking, Jirinec and colleagues analyzed data on nonmigratory birds collected from 1979 to 2019 in an intact region of the Amazon that spans 43 kilometers. The dataset includes measurements such as mass and wing length for over 11,000 individual birds of 77 species. The researchers also examined climate data for the region.
All species declined in mass over this period, the researchers found, including birds as different as the Rufous-capped antthrush (Formicarius colma), which snatches insects off the forest floor, and the Amazonian motmot (Momotus momota), which scarfs down fruit up in trees. Species lost from about 0.1 percent to nearly 2 percent of their average body weight each decade. The motmot, for example, shrunk from 133 grams to about 127 grams over the study period.

These changes coincided with an overall increase in the average temperature of 1 degree Celsius in the wet season and 1.65 degrees C in the dry season. Temperature and precipitation also became more variable over the time period, and these short-term fluctuations, such as an especially hot or dry season, better explained the size trends than the steady increase in temperature.

“The dry season is really stressful for birds,” Jirinec says. Birds’ mass decreased the most in the year or two after especially hot and dry spells, which tracks with the idea that birds are getting smaller to deal with heat stress.

Other factors, like decreased food availability, could also lead to smaller sizes. But since birds with widely different diets all declined in mass, a more pervasive force like climate change is the likely cause, Jirinec says.

Wing length also grew for 61 species, with a maximum increase of about 1 percent per decade. Jirinec thinks that longer wings make for more efficient, and thus cooler, fliers. For instance, a fighter jet, with its heavy body and compact wings, takes enormous power to maneuver. A light and long-winged glider, by contrast, can cruise along much more efficiently.

“Longer wings may be helping [birds] fly more efficiently and produce less metabolic heat,” which can be beneficial in hotter conditions, he says. “But that’s just a hypothesis.” This body change was most pronounced in birds that spend their time higher up in the canopy, where conditions are hotter and drier than the forest floor.

Whether these changes in shape and size represent an evolutionary adaptation to climate change, or simply a physiological response to warmer temperatures, remains unclear (SN: 5/8/20). Whichever is the case, Jirinec suggests that the change shows the pernicious power of human activity (SN: 10/26/21).

“The Amazon rainforest is mysterious, remote and teeming with biodiversity,” he says. “This study suggests that even in places like this, far removed from civilization, you can see signatures of climate change.”

Satellite swarms may outshine the night sky’s natural constellations

Fleets of private satellites orbiting Earth will be visible to the naked eye in the next few years, sometimes all night long.

Companies like SpaceX and Amazon have launched hundreds of satellites into low orbits since 2019, with plans to launch thousands more in the works — a trend that’s alarming astronomers. The goal of these satellite “mega-constellations” is to bring high-speed internet around the globe, but these bright objects threaten to disrupt astronomers’ ability to observe the cosmos (SN: 3/12/20). “For astronomers, this is kind of a pants-on-fire situation,” says radio astronomer Harvey Liszt of the National Radio Astronomical Observatory in Charlottesville, Va.

Now, a new simulation of the potential positions and brightness of these satellites shows that, contrary to earlier predictions, casual sky watchers will have their view disrupted, too. And parts of the world will be affected more than others, astronomer Samantha Lawler of the University of Regina in Canada and her colleagues report in a paper posted September 9 at arXiv.org.

“How will this affect the way the sky looks to your eyeballs?” Lawler asks. “We humans have been looking up at the night sky and analyzing patterns there for as long as we’ve been human. It’s part of what makes us human.” These mega-constellations could mean “we’ll see a human-made pattern more than we can see the stars, for the first time in human history.”
Flat, smooth surfaces on satellites can reflect sunlight depending on their position in the sky. Earlier research had suggested that most of the new satellites would not be visible with the naked eye.

Lawler, along with Aaron Boley of the University of British Columbia and Hanno Rein of the University of Toronto at Scarborough in Canada, started building their simulation with public data about the launch plans of four companies — SpaceX’s Starlink, Amazon’s Kuiper, OneWeb and StarNet/GW — that had been filed with the U.S. Federal Communications Commission and the International Telecommunications Union. The filings detailed the expected orbital heights and angles of 65,000 satellites that could be launched over the next few years.

“It’s impossible to predict the future, but this is realistic,” says astronomer Meredith Rawls of the University of Washington in Seattle, who was not involved in the new study. “A lot of times when people make these simulations, they pick a number out of a hat. This really justifies the numbers that they pick.”

There are currently about 7,890 objects in Earth orbit, about half of which are operational satellites, according to the U.N. Office for Outer Space Affairs. But that number is increasing fast as companies launch more and more satellites (SN: 12/28/20). In August 2020, there were only about 2,890 operational satellites.

Next, the researchers computed how many satellites will be in the sky at different times of year, at different hours of the night and from different positions on Earth’s surface. They also estimated how bright the satellites were likely to be at different hours of the day and times of the year.

That calculation required a lot of assumptions because companies aren’t required to publish details about their satellites like the materials they’re made of or their precise shapes, both of which can affect reflectivity. But there are enough satellites in orbit that Lawler and colleagues could compare their simulated satellites to the light reflected down to Earth by the real ones.

The simulations showed that “the way the night sky is going to change will not affect all places equally,” Lawler says. The places where naked-eye stargazing will be most affected are at latitudes 50° N and 50° S, regions that cross lower Canada, much of Europe, Kazakhstan and Mongolia, and the southern tips of Chile and Argentina, the researchers found.
“The geometry of sunlight in the summer means there will be hundreds of visible satellites all night long,” Lawler says. “It’s bad everywhere, but it’s worse there.” For her, this is personal: She lives at 50° N.

Closer to the equator, where many research observatories are located, there is a period of about three hours in the winter and near the time of the spring and fall equinoxes with few or no sunlit satellites visible. But there are still hundreds of sunlit satellites all night at these locations in the summer.

A few visible satellites can be a fun spectacle, Lawler concedes. “I think we really are at a transition point here where right now, seeing a satellite, or even a Starlink train, is cool and different and wow, that’s amazing,” she says. “I used to look up when the [International Space Station] was overhead.” But she compares the coming change to watching one car go down the road 100 years ago, versus living next to a busy freeway now.

“Every sixteenth star will actually be moving,” she says. “I hope I’m wrong. I’ve never wanted to be wrong about a simulation more than this. But without mitigation, this is what the sky will look like in a few years.”

Astronomers have been meeting with representatives from private companies, as well as space lawyers and government officials, to work out compromises and mitigation strategies. Companies have been testing ways to reduce reflectivity, like shading the satellites with a “visor.” Other proposed strategies include limiting the satellites to lower orbits, where they move faster across the sky and leave a fainter streak in telescope images. Counterintuitively, lower satellites may be better for some astronomy research, Rawls says. “They move out of the way quick.”

But that lower altitude strategy will mean more visible satellites for other parts of the world, and more that are visible to the naked eye. “There’s not some magical orbital altitude that solves all our problems,” Rawls says. “There are some latitudes on Earth where no matter what altitude you put your satellites at, they’re going to be all over the darn place. The only way out of this is fewer satellites.”

There are currently no regulations concerning how bright a satellite can be or how many satellites a private company can launch. Scientists are grateful that companies are willing to work with them, but nervous that their cooperation is voluntary.

“A lot of the people who work on satellites care about space. They’re in this industry because they think space is awesome,” Rawls says. “We share that, which helps. But it doesn’t fix it. I think we need to get some kind of regulation as soon as possible.” (Representatives from Starlink, Kuiper and OneWeb did not respond to requests for comment.)

Efforts are under way to bring the issue to the attention of the United Nations and to try to use existing environmental regulations to place limits on satellite launches, says study coauthor Boley (who also lives near 50° N).

Analogies to other global pollution problems, like space junk, can provide inspiration and precedents, he says. “There are a number of ways forward. We shouldn’t just lose hope. We can do things about this.”

College Football Playoff rankings: Who are the top four teams in fourth CFP poll of 2021?

Two more top-10 teams in contention for the College Football Playoff lost on Saturday, creating yet more work for the selection committee. Well, sort of.

While the committee was forced to reshuffle the rankings after the losses of No. 3 Oregon (38-7 to No. 23 Utah) and No. 7 Michigan State (56-7 to No. 4 Ohio State), those outcomes actually created a more streamlined top 25 in the final weeks of the season.
The selection committee no longer has to explain why No. 6 Michigan ranked ahead of Michigan State, despite the Spartans' head-to-head victory over the Wolverines. Nor do they need to worry about where to rank Oregon, which beat Ohio State in Week 2, well before the Buckeyes' resurgence. The only actual problem created from Saturday's slate of games wasn't even a problem at all: Where to rank Alabama in relation to Ohio State.

The committee chose to push the Buckeyes ahead of the Crimson Tide in the latest rankings. That decision ultimately won't matter, considering Alabama must face No. 1 Georgia in the SEC championship game. A win there would give Nick Saban and Co. the top overall seed. A loss would eliminate the Tide from championship contention.

The committee will pay close attention to "The Game" and Bedlam in Week 13, two rivalry games that feature 10-1 opponents in Ohio State, Michigan, Oklahoma and Oklahoma State. That will further clear up the playoff picture, the final rankings for which are quickly approaching.

With that, here are the top 25 teams in the latest CFP rankings:
College Football Playoff rankings 2021
Who are the top four CFP teams of fourth CFP poll of 2021?
Ranking Team Record
1 Georgia 11-0
2 Ohio State 10-1
3 Alabama 10-1
4 Cincinnati 11-0
Who are the first two teams out of fourth CFP poll of 2021?
Ranking Team Record
5 Michigan 10-1
6 Notre Dame 10-1
CFP top 25 rankings from fourth CFP poll of 2021
Rank Team Record
1 Georgia 11-0
2 Ohio State 10-1
3 Alabama 10-1
4 Cincinnati 11-0
5 Michigan 10-1
6 Notre Dame 10-1
7 Oklahoma State 10-1
8 Baylor 9-2
9 Ole Miss 9-2
10 Oklahoma 10-1
11 Oregon 9-2
12 Michigan State 9-2
13 BYU 9-2
14 Wisconsin 8-3
15 Texas A&M 8-3
16 Iowa 9-2
17 Pittsburgh 9-2
18 Wake Forest 9-2
19 Utah 8-3
20 NC State 8-3
21 San Diego State 10-1
22 UTSA 11-0
23 Clemson 8-3
24 Houston 10-1
25 Arkansas 7-4

Terence Crawford vs. Shawn Porter: A fight that neither can afford to lose

Far too often, fighters say that they can’t afford to lose when they, in fact, can afford to lose.

A loss isn't the end for all fighters and the greatest have come back from significant losses in their career. All losses aren't the same and there's often an overreaction to how much a loss hurts the future of a fighter.
Take, for instance, Canelo Alvarez vs. Caleb Plant. Plant was never expected to win the fight. Of course, he didn’t want to lose and the spoils go to the victor but the concept of a moral victory applied. He made a good showing of himself and will certainly be back, perhaps with more eyeballs on him now than before.

There are rarely fights that neither can afford to lose because of just how devastating to their future the loss would be.

Terence Crawford vs. Shawn Porter on Nov. 20 in Las Vegas is one of those fights.

Why Terence Crawford can’t afford to lose
If Terence Crawford loses to Shawn Porter, the allure is gone. And maybe he wasn’t as good as we thought he was.

Although he was named the Fighter of the Year by ESPN and the Boxing Writers Association of America all the way back in 2014 (and again by ESPN in 2017), the current WBO welterweight champion remains in pursuit of a signature win. The critics have had every right to have their questions because as great as Crawford has looked, his resume lacks that one opponent who is respected for his accomplishments and accolades.

Shawn Porter is that opponent.

A two-time welterweight champion that has given hell to every single opponent that he’s stepped into the ring with. With Manny Pacquiao retired, an argument can be made that Porter has the most impressive resume of every fighter in the 147-pound weight class. And if it wasn’t for Canelo, Porter might have the best resume in all of boxing. Although he hasn’t won all of his big fights, he has yet to be dominated by an opponent.
He’s defeated Danny Garcia, Yordenis Ugas, Adrian Broner while losing narrow decisions to Keith Thurman, Errol Spence Jr. and Kell Brook. As a matter of fact, 11 of his last 13 opponents were world titleholders.

It doesn’t get much better than that. And a Crawford victory opens the door wide open for him to challenge Spence and the rest of the division in an attempt to become undisputed in two division. They won't be able to deny him any longer unless they are scared. It's just that simple.

With all of this being said, one would think that Crawford could afford to lose given Porter’s credentials. Well, that’s certainly not the case. He has hovered as one of the top five pound-for-pound fighters without a marquee name on his resume because he’s been that damn good inside of the squared circle.

But what he hasn’t been is tested by an opponent who has given the best 147-pounders 36 minutes of pressure.
Crawford may have graduated with high honors from his pugilism undergraduate but now he has to prove that he’s Magna Cum Laude and get his master’s degree in the sweet science.

He has an opportunity to barely pass the test like Errol Spence and still be considered as one of the best in the world or he gets mowed down by Porter’s aggressive style and find himself possibly removed from the pound for pound list. Or, he destroys Porter and is undeniably the top dog of the division and once again in the conversation as the best fighter in the world.

Of even more significance is that he’ll be a free agent. It’s no secret that Top Rank has struggled to get him a marquee fight as opponents ranging from Errol Spence Jr., Keith Thurman and the recently retired Manny Pacquiao fought for a rival promotion. There’s an expectation that Crawford will see what’s on the other side of the street if he gets past Porter. But at 34 years of age and facing constant struggles to prove he’s a marketable star, a loss would be devastating to his future.

Bob Arum has spoken in less than flattering terms about Crawford while PBC will have proven their point that Crawford is not in the league of their current stable. Where does Crawford go if he loses all of his leverage?

He cannot afford to lose on Saturday night.

Why Shawn Porter can’t afford to lose
Boxing has been kind to Shawn Porter because Porter has been kind to the sport. He’s a fighter who could care less about politics and risks. He’ll fight anybody at any time. And if you step into the ring with Porter, it will be less fun for you than it is for him. He enjoys plowing into opponents and forcing them to fight his fight. It’s rare to find a Porter fight that lacked excitement and fans have had the opportunity to enjoy Porter’s fearlessness inside of the squared circle.

But, eventually, you have to win the big one.

Porter is a two-time world champion who is 4-3 in major world title bouts. He fell just a hair short against Keith Thurman, Kell Brook and Errol Spence Jr. And while all three of those fights were a round or two away from seeing Porter victorious, the fact remains that he lost. The record books won't explain how close he was and future generations just won't care. The stats are the stats.

The expectation is that Porter will give Crawford all he can handle but fail to get the job done. Oddsmakers have installed him as a significant underdog despite his in-ring accomplishments. This is a sign that many people think that his time is up. And if he ends up proving the naysayers right, the idea that Shawn Porter is one of the best welterweights in the world is likely over.

Simply put, if he loses, he goes from contender to gatekeeper. He becomes the guy that young fighters target as a name for their resume. It’s highly unlikely that he’ll find himself in a marquee fight as the A-side and will spend the rest of his career as an opponent. Jarron "Boots" Ennis and Vergil Ortiz will look to use Porter's name as a stepping stone.

Nobody wants to be a stepping stone. But that's how Porter will be viewed if he is unable to get the job done.

It’s also possible that his hall of fame credentials hinges entirely on this fight.

A victory finds Porter back in the mix and rematches with Yordenis Ugas and Errol Spence Jr. will have to be made. There will be a reason to believe that Porter is absolutely one of the best fighters in the world and he'll certainly crash the pound for pound list with an exceptional performance.

But it all goes up in a cloud of smoke if he loses.

As you can see, the pendulum swing for both fighters is extreme. Neither can afford to lose because their respective futures rely so heavily on what happens inside of those 12 rounds. The stakes are high on both sides and that's more than enough reason to watch what could be an incredible fight with the respective futures of both Crawford and Porter hanging in the balance.

Athlete reactions to Kyle Rittenhouse not guilty verdict by jury

Kyle Rittenhouse has been found not guilty.

A jury in Kenosha, Wisconsin, on Friday found Rittenhouse not guilty of homicide and other charges.
On Aug. 25, 2020, Rittenhouse shot at four men, killing two and wounding a third, with a semiautomatic rifle. Rittenhouse was in downtown Kenosha to protect a car dealership during unrest following the police shooting of Jacob Blake.
Blake, a Black man, had been shot multiple times by Rusten Sheskey, a white police officer, in Kenosha, leaving him paralyzed from the waist down. Sheskey was ultimately not charged by state or federal prosecutors.

Rittenhouse, then a 17-year-old from Antioch, Ill., joined a group of other armed people in downtown Kenosha. He shot Joseph Rosenbaum, Anthony Huber and Gaige Grosskreutz, the latter of whom survived. Rittenhouse turned himself in to police in Antioch on Aug. 26, and was extradited to Kenosha, where he was charged with the following:

First-degree reckless homicide, use of a dangerous weapon
First-degree recklessly endangering safety, use of a dangerous weapon
First-degree intentional homicide, use of a dangerous weapon
Attempted first-degree intentional homicide, use of a dangerous weapon
First-degree recklessly endangering safety, use of a dangerous weapon
Possession of a dangerous weapon by a person under 18 (later dismissed)
Failure to comply with an emergency order from state or local government (later dismissed)
Most of the incident was captured on video, and the subsequent trial became heavily polarized. The prosecution in the case argued that Rittenhouse provoked protesters before shooting at them, while the defense argued that Rittenhouse acted in self defense.

The Milwaukee Bucks are scheduled to play at home tonight at 8 p.m. ET/7 p.m. CT. The Bucks, who play 40 miles from Kenosha, were the first NBA team to boycott following the protests in the summer of 2020.

Following the verdict in the case that captured national attention, the sports world responded to the news that Rittenhouse was ruled not guilty.
Sporting News will continue to monitor and update news from around the sports world as it unfolds.

Luka Doncic injury update: Mavericks superstar listed as doubtful against Suns with ankle injury

A big win over the Denver Nuggets was soured for the Dallas Mavericks in the final minute when Luka Doncic appeared to suffer an ankle injury.

After the game against Denver, Doncic is averaging 24.9 points, 8.3 rebounds and 7.9 assists on the season.

What's next for Doncic? Here's everything we know about his injury and the latest news on when he may return to the court.
What is Luka Doncic's injury?
The injury was sustained as the Mavericks superstar attempted to block an Austin Rivers layup. Rivers' body appeared to roll over the ankle of Doncic in the aftermath of the play.
The win improved Dallas to 9-4 on the season, good for third in the Western Conference.

Doncic was his usual dominant self in the win, finishing with 23 points, eight rebounds, 11 assists, two steals and a block across 37 minutes of play.

How long will Luka Doncic be out?
Doncic was unavailable for media postgame as he was undergoing treatment, with head coach Jason Kidd unable to give an immediate update.

“Luka walked off on his own power,” Kidd said.

“I think he got his lower left leg rolled up on, so we’ll see how he feels.”

The following day, The Athletic's Shams Charania reported that tests on Doncic's left ankle and knee "showed no damage." ESPN's Tim MacMahon added that his injury is believed to be "not too serious" and that he'll likely miss some time but hopefully not an extended stretch.

Doncic sat out the Mavs' loss to the Phoenix Suns on Nov. 17 and is doubtful for the team's rematch on Nov. 19.

Mavericks upcoming schedule 2021-22
Date Opponent Time (ET)
Fri, Nov. 19 at Phoenix 10:00 PM
Sun, Nov. 21 at LA Clippers 3:30 PM
Tue, Nov. 23 at LA Clippers 10:30 PM
Sat, Nov. 27 vs. Washington 8:30 PM
Mon, Nov. 29 vs. Cleveland 8:30 PM
Wed, Dec. 1 at New Orleans 8:00 PM
Doncic has been a durable player throughout the early portion of his career, playing all 13 games this season so far, after missing just six across the 72-game regular season in 2020-21.

Stay tuned for further updates from the team on the status of Doncic and his ankle.

How long is LeBron James out? Injury timeline, return date, latest updates on Lakers star

The Lakers will continue to lean on Anthony Davis and Russell Westbrook early in the 2021-22 season as they move forward without the services of their best player.

Los Angeles star LeBron James has missed the last two weeks of action with an abdominal strain. The four-time NBA MVP was sidelined for two of the Lakers' first eight games of the season before suffering the injury against the Rockets on Nov. 2.
What's next for James? Here's everything we know about his injury and the latest news on when he may return to the court.
What is LeBron James' injury?
The Lakers have listed James as out on recent injury reports with a rectus abdominis strain. That muscle group is "slung between the ribs and the pubic bone at the front of the pelvis," per BetterHealth.com, and its primary function is to "move the body between the ribcage and the pelvis."

An abdominal strain can cause sharp pains and result in difficulty stretching the muscle.
How long will LeBron James be out?
After the Lakers' game, against the Bucks, the first of five on the road, James said 'I hope I hope' when asked about suiting up in the team's next game against the Celtics.

However, ESPN's Dave McMenamin reports that it's a '50-50' chance that James could play on Friday at the TD Garden.

James was initially expected to miss two weeks, according to The Athletic's Shams Charania, who reported on Nov. 4 that the Lakers are taking a cautious approach with his injury.

"If this were the playoffs, could James push to play? Possibly," Charania said. "But James suffered the injury in Tuesday's win over the Rockets, and the Lakers want to be careful and manage the injury during the marathon of this NBA season."
However, Tim DiFrancesco, the Lakers' former head strength and conditioning coach, told The Athletic's Bill Oram that even a minor strain can take several weeks to heal.

"Especially the way he plays, it's tough for me to see him getting back under four weeks," DiFrancesco said. "Then again, he's a different dude, so I wouldn't put anything past him. … These are such delicate injuries that can respond to rest with pain relief quickly, but they are highly susceptible to re-injury if returned too quickly."
Lakers upcoming schedule 2021-22
Date Opponent Time (ET) / Result National TV
Nov. 4 vs. Thunder L, 107-104 —
Nov. 6 at Trail Blazers L, 105-90 NBA TV
Nov. 8 vs. Hornets W, 126-123 (OT) NBA TV
Nov. 10 vs. Heat W, 120-117 (OT) ESPN
Nov. 12 vs. Timberwolves L, 107-83 —
Nov. 14 vs. Spurs W, 114-106 —
Nov. 15 vs. Bulls L, 121-103 NBA TV
Nov. 17 at Bucks 7:30 p.m. ESPN
Nov. 19 at Celtics 7:30 p.m. ESPN
LeBron James stats for 2021-22 season
24.8 points per game
5.5 rebounds per game
7.0 assists per game
2.3 steals per game
4.2 turnovers per game
37.0 minutes per game
46.7 percent shooting
34.7 percent 3-point shooting
78.3 percent free throw shooting

College football coach carousel: Every FBS coaching change in 2021

The 2021 FBS coaching carousel is moving fast, and we're just starting November.

Virginia Tech coach Justin Fuente was fired on Tuesday after six seasons. Fuente is the 12th coaching change in the 2021 season. That list includes seven Power 5 openings. Washington's Jimmy Lake was fired on Sunday.
There were 18 coaching changes last season, a number that likely will be surpassed given how many we've seen so far.

Sporting News looks at all the changes in 2021:

2021 FBS coaching changes
Randy Edsall, UConn
Resigned (Sept. 6): Edsall resigned after the Huskies' 0-2 start. Edsall had two separate stints at UConn. The first, from 1999 to 2010, saw the program make the rise to the FBS ranks and culminated with a trip to the Fiesta Bowl in 2010. Edsall returned in 2017, and that produced a 6-32 record. UConn did not play in 2020 because of COVID-19 concerns. Lou Spanos is the Huskies' interim coach.

Clay Helton, USC
Fired (Sept. 14): Helton, who had been on the hot seat the past few seasons, was fired after the Trojans' 42-28 loss to Stanford in Week 2. Helton replaced Steve Sarkisian in 2015 and compiled a 46-24 record. That mark included the program's last Pac-12 championship in 2017. USC, however, slipped to a 19-14 record from 2018-21. Donte Williams replaced Helton as interim coach.
Chad Lunsford, Georgia Southern
Fired (Sept. 26): Lunsford was fired after a 1-3 start this season. It was a peculiar decision considering the Eagles reached bowl games the previous three seasons. Lunsford compiled a 28-21 record and had previously been an assistant coach with the program from 2013-17. Kevin Whitley was appointed interim coach.

2021 Coaching changes by school
SCHOOL FIRED/RESIGNED REPLACEMENT
UConn Randy Edsall Jim Mora
USC Clay Helton
Georgia Southern Chad Lunsford Clay Helton
LSU Ed Orgeron
Washington State Nick Rolovich
Texas Tech Matt Wells Joey McGuire
TCU Gary Patterson
Akron Tom Arth
UMass Walt Bell
Washington Jimmy Lake
FIU Butch Davis
Virginia Tech Justin Fuente
Ed Orgeron, LSU
Resigned (Oct. 19): Orgeron and LSU reached a separation agreement that will take effect after the conclusion of the 2021 season. This came one day after the Tigers beat Florida 49-42. Orgeron replaced Les Miles in 2016 and became the third consecutive LSU coach to win a national championship (2019). The Tigers finished 15-0 with Heisman Trophy winner Joe Burrow that year, but the program has been a disaster on and off the field since. The problems include a Title IX lawsuit and self-imposed penalties.

Nick Rolovich, Washington State
Fired (Oct. 20): Rolovich was fired in his second season with the Cougars for failing to comply with the state's COVID-19 vaccine mandate. Rolovich cited religious beliefs for his reason to not get the vaccine, and he plans to sue the university over his firing . Rolovich, who previously coached at Hawaii, had a 5-6 record at Washington State. Jake Dickert replaced Rolovich on an interim basis.
Matt Wells, Texas Tech
Fired (Oct. 25): Wells was fired after a 25-24 loss to Kansas State on Oct. 23, which capped an unremarkable three-year stint with the Red Raiders. Wells replaced Kliff Kingsbury, who took a head coaching job in the NFL with the Cardinals. Wells compiled a 13-17 record but appeared to have Texas Tech headed in the right direction this year with a 5-2 start. Sonny Cumbie, a former Red Raiders quarterback, is the interim coach.

Gary Patterson, TCU
Resigned (Oct. 31): Patterson and TCU agreed to part ways after a 3-5 record through the first two months of the season. It's still a somewhat shocking move considering he was the second-longest tenured coach in the FBS behind Iowa's Kirk Ferentz. Patterson took over the Horned Frogs in 2000, and he led the program to six conference championships and 11 seasons with 10 wins or more. The highlight was 2010, when TCU finished 13-0 and won the Rose Bowl. The Horned Frogs moved up to the Big 12 and enjoyed success in the Power 5.

Tom Arth, Akron
Fired (Nov. 4): Arth was fired two days after a 31-25 loss to Ball State dropped the Zips to 2-7 in 2021. Arth, a nearby John Carroll alum, simply could not get Akron going in three seasons. The Zips had a 3-24 record in that stretch, including a 3-17 record in Mid-American Conference play.

Walt Bell, UMass
Fired (Nov. 8): Bell was fired after a 35-22 loss to Rhode Island on Nov. 6. Bell, who took the UMass job after a stint as an offensive coordinator at Florida State, had a 2-23 record since taking over in 2019.

Jimmy Lake, Washington
Fired (Nov. 14): Lake was already under a university suspension for hitting Huskies linebacker Ruperake Fuavai in the helmet druing a game. He did not coach the Huskies' loss to Arizona State on Nov. 13. Earlier that day, The Seattle Times published an article that contained allegations Lake shoved former wide receiver Quinten Pounds into a locker at halftime of a 2019 game at Arizona. Lake denied the allegations. Washington was 7-6 under Lake. Assistant coach Bob Gregory was named interim head coach.

Butch Davis, FIU
Fired (Nov. 15): Davis will not return to FIU when his contract expires at the end of this season. The decision comes a week after longtime FIU athletic director Pete Garcia resigned. Davis said the school administration is "sabotaging the program." Davis, who previously coached at Miami and North Carolina, had success in his first two seasons at FIU. The program slipped the last two years, however, and is 1-9 in 2021.

Justin Fuente, Virginia Tech
Fired (Nov. 16): Fuente is out after six seasons with the Hokies. Fuente, who was hired in 2016 after a three-year stint in Memphis, enjoyed a 10-4 season and an appearance in the ACC championship game in his first season. The Hokies are 24-23 the last four years, however, and they have been a middle-of-the-road program in the ACC Coastal Division. Fuente finshed with a record of 43-31.