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As of March 18 this year, Boeing's stock price had fallen by 28 percent, while the international rating agency Fitch Ratings stated that Boeing's default risk is gradually approaching junk bond status.

The American news website Quartz recently sorted out "A timeline of Boeing's brutal 2024 (so far)." On January 5, a Boeing 737 Max jetliner's built-in emergency door fell off, starting Boeing's "chaotic year." Subsequently, from February 6 to March 15, there were at least five safety incidents, including a stuck rudder pedal, wheel detachment, rapid air descent, a tire explosion, and missing external panels. On March 9, the death of former Boeing employee John Barnett, who had previously exposed serious deficiencies in Boeing's oxygen system, also sparked media speculation.

Industry insiders and experts reached by the Global Times revealed that behind the frequent incidents is the American hegemony that has fallen apart like scattered nuts and bolts on the floor. The serious safety problems of the head of the US aerospace industry and the world's leading manufacturer of civil and military aircraft have also made the US media, scholars and the public think of the long-standing systemic problems in the country's manufacturing industry, and reflect on the entire trajectory of "deindustrialization" and "re-industrialization" in the US.
Competitive pressure

Chinese student Li Yu, who lives in St. Louis, Missouri, where Boeing has a factory and is one of the local pillar industries, told the Global Times that she often encounters Boeing employees attending advanced training classes at the university.

Although she has heard of the recent incidents, Li admitted that in the US, it is difficult to avoid Boeing planes for most people when traveling.

"When taking a plane, although I feel uneasy, I can only grit my teeth and go through with it," Li said.

A former airline employee from Georgia told the Global Times that the majority of the planes used by airlines in the US are Boeing planes, many of which are quite old. Airlines have detailed operating instructions for Boeing planes, and he guessed that the airlines involved in the recent incidents might not have maintained the Boeing planes as directed.

"It's as if I'm watching a troubled child," said Captain Dennis Tajer, the lead spokesman of the Allied Pilots Association, when describing flying a Boeing 737 Max, according to BBC.

Tajer stated that if the plane is not safe, he would never board it, and he can no longer assume that the planes he pilots are of good quality.

However, according to the American online media outlet Axios, US Secretary of Transportation Pete Buttigieg has made continued attempts to assure the US public that flying is as safe as ever. In Buttigieg's view, the "real concerns" are Boeing's quality control, but he would still sit by the window on a Boeing plane.

According to the American Forbes magazine website, fortunately, there have been no fatalities due to Boeing plane malfunctions in recent weeks. However, five years ago, within nearly five months, two crashes involving Boeing 737 Max jets occurred in Indonesia and Ethiopia, killing 346 people.

In September 2021, PBS's Frontline channel and The New York Times co-produced a documentary titled "Boeing's Fatal Flaw," which, after an in-depth investigation, revealed the systemic causes behind the Boeing crash incidents - competitive pressure, inadequate pilot training, and regulatory absence.

According to the documentary, the 737 Max model was born under intense competitive pressure. In 2011, Airbus launched the new, more energy-efficient, and higher-efficiency model A320neo, and reached a preliminary agreement with a US airline, marking the airline's first order with Airbus in over a decade. Under this pressure, Boeing urgently initiated the design program for the 737 Max model.

Former employees involved in the work revealed that Boeing executives consistently pressured the staff to design the new model "faster, better, and cheaper," continually trying to reduce costs and minimize changes to the new plane to simplify pilot training differences, and to get the new model to market as quickly as possible.

The Federal Aviation Administration (FAA), which was supposed to regulate Boeing, authorized some of the safety inspection work to Boeing's own employees, leading to numerous cover-ups.

Increased risks

In this year's safety issues with Boeing, the far-reaching impact of the aforementioned systemic problems is still evident.

Analysts noted that Boeing's decline is the result of prioritizing profits over decades. Jack Welch, former CEO of General Electric, who influenced Boeing's culture with his "lean management" philosophy, focused on cutting manufacturing processes and workforce to boost stock prices.

Boeing's excessive reliance on outsourcing, as reported by The Wall Street Journal in January, has also led to safety issues and increased risks, with critical components being manufactured globally.
Moreover, interviews with industry executives revealed that production pressure and loss of experienced workers caused further problems. Boeing, needing to meet growing aircraft demand, reduced quality checks while prioritizing production speed, Reuters reported.

The international logistics media site Polar Star reported that the US aviation industry has long been troubled by supply chain issues. Many parts are in short supply, with delivery times for some metal parts and windshields being 2 to 5 times longer than normal.

The shortage of aircraft mechanics and other aviation industry professionals also strains the supply chain. Media reports say that some machine shops have sophisticated equipment but lack the labor to operate it, making licensed aircraft mechanics "as rare as unicorns," citing local experts.

Similar dilemmas

Shen Yi, director of the Research Institution for Global Cyberspace Governance at Fudan University, told the Global Times that the frequent Boeing incidents actually manifest the falling of US hegemony.

Boeing, based on neoliberal business and management concepts, once enjoyed the dividends of the Cold War. Now the company has shifted its focus from quality control to cost control, Shen said.

He pointed out that additionally, the US government, driven by the so-called "identity politics" movements that emphasize diversity and equality, has made technical skills, capabilities, and experience secondary factors in personnel selection and appointment.

Therefore, after a period of sedimentation and accumulation, the lack of focus on the expertise has led to the increase in safety-related accidents this year, he noted.

Recently, the US magazine Foreign Affairs published an article pointing out the problem of the "privatization and the hollowing out of the US defense industry." In addition to the defense field, many other manufacturing sectors are reportedly facing similar troubles.

According to the Financial Times, the decline of the US shipbuilding industry is causing anxiety in the US. Industry insiders widely attribute this decline to several factors. First, in the 1980s, the Reagan administration pursued a free-market economy and thus eliminated most subsidies for the shipbuilding industry. US defense officials and unions have stated that due to the shrinking domestic manufacturing base and outsourcing, a significant portion of the materials and components needed to produce new ships are no longer available domestically. And this is also happening in other manufacturing sectors.

In addition, due to the "just-in-time" production methods adopted in recent decades, US contractors are reluctant to maintain redundant capacity. Furthermore, industry consolidation and the rise of shipbuilding industries in Japan, South Korea, and China have led to reduced investment in technology, factory equipment, and worker training in the US, according to the article.

Analysts pointed out that the real issue with US labor is its low productivity as workers have long demanded high wages and work-life balance. Moreover, the infrastructure conditions in the US are not promising.

Reports showed that much of the existing infrastructure in the US was built in the 1960s. Therefore, much of it is virtually defunct.

While the US Congress passed the Bipartisan Infrastructure Deal (Infrastructure Investment and Jobs Act) in 2021, the real process of upgrading the infrastructure is slow as there is no consensus on funding and building.
Misplaced obsession

According to the 2024 manufacturing industry outlook issued by Deloitte, the manufacturing sector in the US will continue to face challenges this year. However, several US media outlets and think tanks are optimistic about the country's manufacturing industry.

In October 2023, the Cato Institute, a US think tank, published an analysis titled "The Reality of American Deindustrialization," arguing that "American manufacturing has not disappeared but has undergone a transformation instead."

While US politicians have been actively advocating for the reviving of manufacturing, an article published by The Hill pointed out that "unfortunately, this obsession with manufacturing is misplaced."

"This manufacturing subsidy war will be expensive and will support inefficient sectors, raising costs for households and firms. For example, most estimates of semiconductor chip fabrication in the US are that it costs up to 50 percent more than fabrication elsewhere. American taxpayers will eventually bear the cost of subsidizing this kind of relative inefficiency," it said.

Several experts told the Global Times that reviving the manufacturing industry requires good infrastructure, research and development investment, industrial support, a continuous supply of adaptable labor, as well as a global network supporting the supply chain and trade value chain.

Even the US, once known as the "world's factory," would find it difficult to fill the gap and revive its manufacturing sector, Zhang Yugui, dean of School of Economics and Finance in Shanghai International Studies University, told the Global Times.

"If the US tries to revitalize its manufacturing industry, it must abandon the zero-sum game mentality and instead form an effective division of labor and cooperation with major manufacturing powers such as China, Europe, Japan, and emerging economies. It should not continue to artificially build 'small yard and high fence'. However, even if some advanced manufacturing industries are lured back to the US, it would be a short-sighted strategy that is unlikely to succeed, Zhang noted.

German Foreign Minister Annalena Baerbock's ongoing visit to Australia, New Zealand and Fiji in the South Pacific is a way of balancing the impact of German Chancellor Olaf Scholz's China trip, which exposed deep political divisions within the German government, said Chinese analysts when commenting on Baerbock's recent remarks in which she warned against becoming too reliant on China.

While Scholz recently visited China and reached many positive agreements, Germany's foreign and economic departments, controlled by the far-right Greens, have been at odds with the Social Democratic Party led by Scholz, especially on China policy, which could affect China-Germany cooperation and hinder Germany's own economic and social recovery, analysts warned. At the same time, they believe sustainable cooperation remains the dominant factor in China-Germany relations.

According to a report by the German Press Agency (DPA), Baerbock is setting off on a week-long visit to Australia, New Zealand and Fiji, and is using the trip to send a message to China, the report said.

During her visit to Australia, which was her first to the country, Baerbock said Germany has overhauled its strategic approach to China to avoid a repeat of the past when the NATO member failed to realize the extent of its economic dependence on Russia, Australian media outlet ABC reported on Sunday.

Baerbock, who is a Greens politician within Chancellor Scholz's coalition, said Germany has now developed a comprehensive China policy to diversify its supply chains, while maintaining a strong trade relationship with Beijing, ABC reported.

Baerbock set off on the South Pacific trip just weeks after Scholz concluded his China trip in April. Analysts said Scholz's "high-profile" visit to China was a return to the normalcy of bilateral relations.

It is clear that Baerbock rushed to visit the South Pacific in order to strike a "diplomatic balance" on China policy, Liu Zuokui, a research fellow on European studies at the Chinese Academy of Social Sciences, told the Global Times on Monday.

Now, more and more people and corporations in the international community are increasingly focusing on and optimistic about China's market and economic potential, a sentiment shared by Scholz, who aims to lead Germany in developing close cooperation with China, Liu said.

However, Baerbock and her far-right party are heavily biased in ideology, prioritizing values and security risks over economic cooperation, conflicting with Scholz's advocacy for pragmatic cooperation with China, Liu noted.

As a result, cooperation between Germany and China could face various disruptions, something that is supported and welcomed by the US, Liu warned. He noted that the German federal elections next year will be crucial in determining whether the German government can effectively manage these internal political struggles and contradictions.

"However, we believe that the closeness of business and economic cooperation will always remain the mainstream in China-Germany relations," Liu stressed.

Germany has been China's largest trading partner in Europe for 49 consecutive years, while China has been Germany's largest global trading partner for eight consecutive years. The facts show that practical cooperation is not just an option, but a necessity.

Also during Baerbock's visit to New Zealand on Saturday, the foreign minister did not rule out the possibility of a German frigate crossing the Taiwan Straits, DPA reported.

According to DPA, German frigate Baden-Württemberg and a supply ship will set off on Tuesday on a training mission to the Pacific lasting several months. The vessels will enter the Pacific Ocean through the Panama Canal and later also cross the South China Sea.

In 2021, German frigate Bayern took part in maneuvers with allies at the time, but avoided Taiwan during its voyage to the Pacific, DPA reported.

If the German frigate crosses the Taiwan Straits, it would be a very dangerous and irrational move for China-Germany relations, Chinese analysts warned. They said hyping the Taiwan question will not bring any benefits to Germany, but will only disrupt the normal development of its ties with China and affect Germany's national interests.

Politicians like Baerbock are trying to gain domestic votes by hyping up the Taiwan question, as those politicians' considerations are more focused on personal and party interests rather than their country's interests, Liu believes.

If German frigates were to cross the Taiwan Straits, China would likely respond resolutely and forcefully, Liu said.

Yumai used to be a township with only one family of three people.

The small village in Lhunze county, Shannan Prefecture, Southwest China's Xizang Autonomous Region, used to be the smallest township population-wise in China.

Nowadays, thanks to improved transportation and infrastructure, the remote area has undergone a transformation. The streets and alleys are clean and tidy, with two-story Tibetan-style buildings that show elegance and charm at the foot of a mix of green and snow mountains.

Today, over 200 residents call this place home. They run a variety of businesses, including shops, restaurants, family inns, and teahouses. Local people wear confident and proud expressions on their faces as they warmly welcome visitors.

Yumai has become the epitome of how China's border regions have dramatically developed.

The story of Yumai begins with the family of three: Sangye Chopa, the household's father; and his daughters Drolkar and Yangzom. Sangye Chopa was the first head of the township.

In the 1950s and 1960s, Yumai, with its harsh natural conditions and extremely poor transportation, presented a formidable challenge. In 1964, Sangye Chopa, along with his wife and daughters, embarked on a challenging journey, crossing snowy mountains with a herd of cattle, to settle in Yumai.

Today, next to the Yumai township government, the Sangye Chopa Residence Memorial Hall faithfully recreates the poor living conditions of this family back in the day when they had to dry firewood in the damp and cold environment of Yumai.

Between 1964 and 1996, the Sangye Chopa family was the only household in this vast territory of Yumai. For over half a century, this father and his two daughters guarded thousands of square kilometers of the motherland. The national flag they sewed by hand flew proudly in the remote southwestern regions of China.

Yumai's development has never ceased. In 1996, the first group of resettlement families arrived in Yumai, consisting of two households made up of 11 individuals.

In 2001, before Sangye Chopa passed away, a road leading to Yumai was finally completed, ending the township's history of no road access, and the first car entered the town. In 2003, Yumai had its first telephone.

In 2017, through a reply letter, Chinese President Xi Jinping encouraged the family of Drolkar and Yangzom, to set down roots in the border area, safeguard the Chinese territory and develop their hometown. Xi hoped that the family would motivate more herders to set down roots in the border area "like galsang flowers," and become guardians of the Chinese territory and constructors of a happy hometown.

In 2019, Yumai was officially designated as a model township for achieving happiness, beauty, and a comfortable life. In April of the same year, a new group of resettlement households arrived in Yumai, increasing the population to 56 households for a total of 191 individuals. On July 3, 2020, a new road leading to Yumai was completed, putting an end to the township's history of being cut off by heavy snow for over six months of the year.

Currently, there are more than 230 people in 67 households living in Yumai township, and its infrastructure, including the electricity grid, roads, 5G network, medical care and financial services facilities, have all been improved.

The giant red slogan on the hillside that reads "Home is Yumai, country is China" is now the most famous landmark in Yumai. These were the words once spoken by Sangye Chopa, and now represents the spirit of people guarding Yumai.

"When I was young, my only playmate was my grandpa Sangye Chopa," Yangzom's son, Sonam Dondrup recalled while taking with the Global Times on Wednesday. "I never imagined life in Yumai could be like this today, nor had my grandpa."

"To me, the biggest change is school. I used to cross two mountains to go to school, which would take me three days," Sonam Dondrup said. "But now, children go to kindergarten right in our town, a couple of steps from home."

At the school in Yumai, the Global Times reporters observed several children playing on the slides and chasing each other in a warm, spacious, and brightly colored playground enclosed by glass walls. Upstairs, in a second-grade classroom with only six students, children were learning a Tibetan pop song expressing gratitude to their parents.

Pedma Tsamjo moved to Yumai in 2019. He runs a family hotel with his wife. "In border regions there are good policies for residents, that was why we moved here," in the cozy, well-decorated living room, Pedma Tsamjo told the Global Times, adding that all the subsidies combined for each adult amount to 30,000 yuan ($4,651) per year.

Pedma Tsamjo's family was sitting around the fireplace, watching martial arts dramas on a smart television, while his child slept beside them. In another year, she will also be able to attend the nearby kindergarten.

In 2022, the per capita annual income in Yumai township reached nearly 44,000 yuan, and the average living space per person was 40 square meters, the Xinhua News Agency reported.

Since 2012, border villages, townships, and counties in Xizang region have benefited from more preferential policies for infrastructure construction, covering water, electricity, roads, and housing, according to the white paper, Tibet Since 1951: Liberation, Development, and Prosperity, published by China's State Council Information Office in May 2021.

The elections of the Taiwan region are China's internal affairs and regardless of the result, it will not change the basic fact that Taiwan is part of China and there is only one China in the world, Chinese Foreign Ministry spokesperson Mao Ning said at a press conference on Friday.

Mao's remarks came in response to a question about how the results of the regional leader election on the island of Taiwan, scheduled on Saturday, will affect the cross-Straits relations.

During the press conference, a reporter also mentioned an anonymous official from the White House reportedly said that the US is committed to the one-China policy, does not support "Taiwan independence" and supports cross-Straits dialogue.

Mao said that the one-China principle is a prevailing international consensus and the political foundation of the China-US relationship. "Taiwan independence" is the biggest threat to cross-Straits peace and stability and is doomed to failure.

US leaders have repeatedly said that they are committed to the one-China policy, do not support "Taiwan independence," do not support "two Chinas" or "one China, one Taiwan," and do not seek to use the Taiwan question as a tool to contain China, said Mao.

We hope the US will honor these commitments, handle Taiwan-related issues prudently and properly, stop official interactions with Taiwan, stop sending wrong signals to "Taiwan independence" separatist forces, and refrain from interfering in the elections of the Taiwan region in any form, the spokesperson said.

If the US truly hopes to safeguard peace and stability in the Taiwan Strait, it needs to explicitly oppose "Taiwan independence" and support China's peaceful reunification, said Mao.

China's central bank and top financial regulator on Friday issued a guideline on stepping up financial support for the housing rental market, vowing to offer more innovative credit products and services for housing rentals and to expand financing channels for the housing rental market.

The guideline from the People's Bank of China (PBC) and the National Administration of Financial Regulation (NAFR) is the latest effort by Chinese policymakers to stabilize the real estate market, by both defusing risks and meeting housing needs for key population groups such as young workers.

The guideline contains a total of 17 measures in four areas. Financial support will focus on key areas and weak links in the housing rental market, mainly in large cities, and will focus on addressing housing difficulties for groups such as new urban residents and young workers.

The guideline aims to offer financial support for various entities to build, renovate and operate long-term rental housing, revitalize exiting housing inventory, and increase the supply of affordable and commercial rental housing.

Among the main measures, the guideline, which was sent to the PBC and the NAFR's local branches and various types of banks, calls for an increase in credit support for housing rental development and construction. Commercial banks are being encouraged to extend loans for entities, including real estate developers, for developing and constructing rental housing projects. The standard loan term would be three years and will not exceed five years.

On the purchasing side, the guideline also encouraged commercial banks to extend loans for entities that purchase housing rental for employees. The term for such loans cannot exceed 30 years and the amount should not exceed 80 percent of the property value.

China has made stabilizing the real estate market a top priority for economic work in 2024. The tone-setting Central Economic Work Conference held in December called for active and prudent efforts to defuse risks in the property sector, address the reasonable financing needs of real estate enterprises, and accelerate the development of a new model for the real estate sector.

Also on Friday, following a national central bank meeting, the PBC vowed to actively support the stable and sound development of the real estate market, strengthen monitoring, and take various credit policies to meet the reasonable financial needs of various types of real estate companies.

The China Academy of Art has welcomed the celebration of its 95th anniversary since its ­establishment in the recently inaugurated Liangzhu campus in East ­China's Zhejiang Province. As the nation's first comprehensive national institution for higher artistic education, the art academy mirrors the evolution of contemporary Chinese art and artistic education over the last century.

Gao Shiming, president of the academy, told the Global Times that Chinese President Xi Jinping's emphasis on the need to combine fine traditional culture with the Marxist stand, viewpoint and approach, also known as the "second integration," holds significant implications for art education. In addition, humanity is entering the "second Renaissance," to which China is making global contributions. 

At a meeting on cultural inheritance and development in June, Xi called for the integration of the basic tenets of Marxism with traditional Chinese culture, known as the "second integration," which builds on the Communist Party of China's "first integration" of theoretical synthesis - the integration of the basic tenets of Marxism with China's specific reality, the Xinhua News Agency reported.

Ma Yifu, a renowned Chinese scholar, once asserted that Marxism has reactivated a socialist gene that exists in Chinese traditional cultural thought and social history, Gao said. 

Common core values

Traditional Chinese culture and Marxism share common core values, such as the concept of equality. Chinese philosopher Wang Yangming's proposal of "cultivating moral consciousness, envisioning every individual as a saint," aligns with Marx's perspective on equality.

Similarly, the integration of Marxism and China's fine traditional culture has been vividly manifested in Chinese art, placing the people at the center and elevating them as the social subjects.

For instance, in the 1950s and 1950s, the Zhejiang school of figure painting, led by Fang Zengxian, employed techniques traditionally used for emperors, bodhisattvas and flora to portray ordinary farmers. This marked a significant period in China's millennia-old art history.

From its inception, the China Academy of Art envisioned an academic mission of "introducing Western art, organizing Chinese art, reconciling Eastern and Western art, and creating contemporary art." Over the last 95 years, the institution has walked alongside the history of modern Chinese art, responding to national crises and reinventing itself in the face of contemporary challenges.

During this period, two scholarly ideas have consistently unfolded: One represented by the inaugural dean, Lin Fengmian, which embodies the "integration of Chinese and Western styles." The other school of thought, pioneered by figures like Huang Binhong and Zhao Wuji, follows the path of "innovation within tradition." Zhao created a form of modern painting from within the folds of Chinese tradition. He activated certain elements of Chinese tradition by using modern art, creating an alternative, distinct and unique form of modern painting that gained global recognition.

"The last 95 years have seen the China Academy of Art charting a path in modern art education deeply rooted in the Chinese soil, reflecting a journey of artistic revival that is both grounded in tradition and independently innovative," Gao said. 

What does a Renaissance require? "Prosperous technology, flourishing arts, developed commerce and a gathering of talents - we have all these elements now," Gao said.

'Second Renaissance'

He explained that the first Renaissance was catalyzed by an external factor - the Age of Discovery. Today, the internet serves as the great navigation of the 21st century. People in the world are not just witnessing a Renaissance in China but a global Renaissance in which China has started contributing to the world. 

In the 21st century, art education in China has taken on a more significant role, serving as a catalyst for societal innovation. The current Chinese society craves innovation, creativity and self-transcendence. Igniting the primitive innovative capabilities of the entire nation is crucial. 

"I often tell students not to confine themselves to being artists within the art realm but to become artists of the world," Gao said, adding that contemporary society demands the need for not just traditional artists but countless art professionals with the ability to innovate and imagine, solving real-world problems. This is the fundamental goal of the China Academy of Art - to foster a culture in which the entire art community contributes to the construction of a beautiful China and the high-quality development of the nation.

In the era of the first ­Renaissance, the world was not peaceful. Today, the world faces constant conflicts, making culture and art even more crucial as forces of reflection and reconciliation, guiding people into a more essential and expansive realm, allowing humanity a sense of transcendence.

The great French writer Flaubert once said, "Art and science met at the foot of the mountain and parted ways at the summit." The difficulty lies in people's journey not yet "reaching the summit," as people have technologized science and turned tools into technology. 

Gao believes there's no need to rush; scientists and artists can engage in more philosophical exchanges. Simultaneously, people can start with specific initiatives, such as promoting a course called "illusion." 

Scientists delve into the internal and physiological mechanisms of illusions, while artists design various illusions. This is a tangible course ­illustrating the fusion of science and art. 

From another perspective, in the era of general artificial intelligence, people might leverage AI to become individuals with more extensive space and creative capabilities, akin to Da Vinci's versatility. 

"As artificial intelligence advances, human artistic intelligence also grows," he said.

Frog brains get busy long before they’re fully formed. Just a day after fertilization, embryonic brains begin sending signals to far-off places in the body, helping oversee the layout of complex patterns of muscles and nerve fibers. And when the brain is missing, bodily chaos ensues, researchers report online September 25 in Nature Communications.

The results, from brainless embryos and tadpoles, broaden scientists’ understanding of the types of signals involved in making sure bodies develop correctly, says developmental biologist Catherine McCusker of the University of Massachusetts Boston. Scientists are familiar with short-range signals among nearby cells that help pattern bodies. But because these newly described missives travel all the way from the brain to the far reaches of the body, they are “the first example of really long-range signals,” she says.
Celia Herrera-Rincon of Tufts University in Medford, Mass., and colleagues came up with a simple approach to tease out the brain’s influence on the growing body. Just one day after fertilization, the scientists lopped off the still-forming brains of African clawed frog embryos. These embryos survive to become tadpoles even without brains, a quirk of biology that allowed the researchers to see whether the brain is required for the body’s development.
The answer was a definite — and surprising — yes, Herrera-Rincon says. Long before the brain is mature, it’s already organizing and guiding organ behavior, she says. Brainless tadpoles had bungled patterns of muscles. Normally, muscle fibers form a stacked chevron pattern. But in tadpoles lacking a brain, this pattern didn’t form correctly. “The borders between segments are all wonky,” says study coauthor Michael Levin, also of Tufts University. “They can’t keep a straight line.”
Nerve fibers that crisscross tadpoles’ bodies also grew in an abnormal pattern. Levin and colleagues noticed extra nerve fibers snaking across the brainless tadpoles in a chaotic pattern, “a nerve network that shouldn’t be there,” he says.

Muscle and nerve abnormalities are the most obvious differences. But brainless tadpoles probably have more subtle defects in other parts of their bodies, such as the heart. The search for those defects is the subject of ongoing experiments, Levin says.
In addition to keeping patterns on point, the young frog brain may protect its body from chemical assaults. A molecule that binds to certain proteins on cells in the body had no effect on normal embryos. But when given to brainless embryos, the same molecule caused their spinal cords and tails to grow crooked. These results suggest that early in development, brains keep embryos safe from agents that would otherwise cause harm.

“The brain is instructing cells that are really a long way away from it,” Levin says. While the precise identities of these long-range signals aren’t known, the researchers have some ideas. When brainless embryos were dosed with a drug that targets cells that typically respond to the chemical messenger acetylcholine, the muscle pattern improved. Similarly, the addition of a protein called HCN2 that can tweak the activity of cells also seemed to improve muscle development. More work is needed before scientists know whether these interventions are actually mimicking messaging from the early brain, and if so, how.

Frog development isn’t the same as mammalian development, but frog development “is pretty applicable to human biology,” McCusker says. In fundamental ways, humans and frogs are built from the same molecular toolbox, she says. So the results hint that a growing human brain might also interact similarly with a growing human body.

The weird glowing blob of gas known as Hanny’s Voorwerp was a 10-year-old mystery. Now, Lia Sartori of ETH Zurich and colleagues have come to a two-pronged solution.

Hanny van Arkel, then a teacher in the Netherlands, discovered the strange bluish-green voorwerp, Dutch for “object,” in 2008 as she was categorizing pictures of galaxies as part of the Galaxy Zoo citizen science project.

Further observations showed that the voorwerp was a glowing cloud of gas that stretched some 100,000 light-years from the core of a massive nearby galaxy called IC 2497. The glow came from radiation emitted by an actively feeding black hole in the galaxy.
To excite the voorwerp’s glow, the black hole and its surrounding accretion disk, the active galactic nucleus, or AGN, should have had the brightness of about 2.5 trillion suns; its radio emission, however, suggested the AGN emitted the equivalent of a relatively paltry 25,000 suns. Either the AGN was obscured by dust, or the black hole slowed its eating around 100,000 years ago, causing its brightness to plunge.

Sartori and colleagues made the first direct measurement of the AGN’s intrinsic brightness using NASA’s NuSTAR telescope, which observed IC 2497 in high-energy X-rays that cut through the dust.

They found that the AGN is obscured by dust and it is dimmer than expected; the feeding has slowed way down. The team reported on arXiv.org on November 20 that IC 2497’s heart is as bright as 50 billion to 100 billion suns, meaning it dropped in brightness by a factor of 50 in the past 100,000 years — a less dramatic drop than previously thought.
“Both hypotheses that we thought before are true,” Sartori says.

Sartori plans to analyze NuSTAR observations of other voorwerpjes to see if their galaxies’ black holes are also in the process of shutting down — or even booting up.

“If you look at these clouds, you get information on how the black hole was in the past,” she says. “So we have a way to study how the activity of supermassive black holes varies on superhuman time scales.”

Editor’s note: This story was updated December 5, 2017, to clarify that the brightness measured by the researchers came from the accretion disk around an actively eating black hole, not the black hole itself.

Out of the hundreds of species of carnivorous plants found across the planet, none attract quite as much fascination as the Venus flytrap. The plants are native to just a small section of North Carolina and South Carolina, but these tiny plants can now be found around the world. They’re a favorite among gardeners, who grow them in homes and greenhouses.

Scientists, too, have long been intrigued by the plants and have extensively studied the famous trap. But far less is known about the flower that blooms on a stalk 15 to 35 centimeters above — including what pollinates that flower.
“The rest of the plant is so incredibly cool that most folks don’t get past looking at the active trap leaves,” says Clyde Sorenson, an entomologist at North Carolina State University in Raleigh. Plus, notes Sorenson’s NCSU colleague Elsa Youngsteadt, an insect ecologist, because flytraps are native to just a small part of North and South Carolina, field studies can be difficult. And most people who raise flytraps cut off the flowers so the plant can put more energy into making traps.

Sorenson and Youngsteadt realized that the mystery of flytrap pollination was sitting almost literally in their backyard. So they and their colleagues set out to solve it. They collected flytrap flower visitors and prey from three sites in Pender County, North Carolina, on four days in May and June 2016, being careful not to damage the plants.

“This is one of the prettiest places where you could work,” Youngsteadt says. Venus flytraps are habitat specialists, found only in certain spots of longleaf pine savannas in the Carolinas. “They need plenty of sunlight but like their feet to be wet,” says Sorenson. In May and June, the spots of savanna where the flytraps grow are “just delightful,” he says. And other carnivorous plants can be found there, too, including pitcher plants and sundews.
The researchers brought their finds back to the lab for identification. They also cataloged what kind of pollen was on flower visitors, and how much.
Nearly 100 species of arthropods visited the flowers, the team reports February 5 in American Naturalist. “The diversity of visitors on those flowers was surprising,” says Youngsteadt. However, only three species — a sweat bee and two beetles — appeared to be the most important, as they were either the most frequent visitors or carriers of the most pollen.
The study also found little overlap between pollinators and prey. Only 13 species were found both in a trap and on a flower, and of the nine potential pollinators in that group, none were found in high numbers.

For a carnivorous plant, “you don’t want to eat your pollinators,” Sorenson says. Flytraps appear to be doing a good job at that.

There are three ways that a plant can keep those groups separate, the researchers note. Flowers and traps could exist at different times of the year. However, that’s not the case with Venus flytraps. The plants produce the two structures at separate times, but traps stick around and are active during plant flowering.

Another possibility is the spatial separation of the two structures. Pollinators tend to be fliers while prey were more often crawling arthropods, such as spiders and ants. This matches up with the high flowers and low traps. But the researchers would like to do some experiments that manipulate the heights of the structures to see just how much that separation matters, Youngsteadt says.

The third option is that different scents or colors produced by flowers and traps might lure in different species to each structure. That’s another area for future study, Youngsteadt says. While attraction to scent and color are well documented for traps, little is now known about those factors for the flowers.

Venus flytraps are considered vulnerable to extinction, threatened by humans, Sorenson notes. The plant’s habitat is being destroyed as the population of the Carolinas grows. What is left of the habitat is being degraded as fires are suppressed (fires help clear vegetation and keep sunlight shining on the flytraps). And people steal flytraps from the wild by the thousands.

While research into their pollinators won’t help with any of those threats, it could aid in future conservation efforts. “Anything we can do to better understand how this plant reproduces will be of use down the road,” Sorenson says.

But what really excites the scientists is that they discovered something new so close to home. “One of the most thrilling parts of all this,” Sorenson says, “is that this plant has been known to science for [so long], everyone knows it, but there’s still a whole lot of things to discover.”

The computer will see you now.

Artificial intelligence algorithms may soon bring the diagnostic know-how of an eye doctor to primary care offices and walk-in clinics, speeding up the detection of health problems and the start of treatment, especially in areas where specialized doctors are scarce. The first such program — trained to spot symptoms of diabetes-related vision loss in eye images — is pending approval by the U.S. Food and Drug Administration.

While other already approved AI programs help doctors examine medical images, there’s “not a specialist looking over the shoulder of [this] algorithm,” says Michael Abràmoff, who founded and heads a company that developed the system under FDA review, dubbed IDx-DR. “It makes the clinical decision on its own.”
IDx-DR and similar AI programs, which are learning to predict everything from age-related sight loss to heart problems just by looking at eye images, don’t follow preprogrammed guidelines for how to diagnose a disease. They’re machine-learning algorithms that researchers teach to recognize symptoms of a particular condition, using example images labeled with whether or not that patient had that condition.
IDx-DR studied over 1 million eye images to learn how to recognize symptoms of diabetic retinopathy, a condition that develops when high blood sugar damages retinal blood vessels (SN Online: 6/29/10). Between 12,000 and 24,000 people in the United States lose their vision to diabetic retinopathy each year, but the condition can be treated if caught early.
Researchers compared how well IDx-DR detected diabetic retinopathy in more than 800 U.S. patients with diagnoses made by three human specialists. Of the patients identified by IDx-DR as having at least moderate diabetic retinopathy, more than 85 percent actually did. And of the patients IDx-DR ruled as having mild or no diabetic retinopathy, more than 82.5 percent actually did, researchers reported February 22 at the annual meeting of the Macula Society in Beverly Hills, Calif.

IDx-DR is on the fast-track to FDA clearance, and a decision is expected within a few months, says Abràmoff, a retinal specialist at the University of Iowa in Iowa City. If approved, it would become the first autonomous AI to be used in primary care offices and clinics.

AI algorithms to diagnose other eye diseases are in the works, too. An AI described February 22 in Cell studied over 100,000 eye images to learn the signs of several eye conditions. These included age-related macular degeneration, or AMD — a leading cause of vision loss in adults over 50 — and diabetic macular edema, a condition that develops from diabetic retinopathy.

This AI was designed to flag advanced AMD or diabetic macular edema for urgent treatment, and to refer less severe cases for routine checkups. In tests, the algorithm was 96.6 percent accurate in diagnosing eye conditions from 1,000 pictures. Six ophthalmologists made similar referrals based on the same eye images.

Researchers still need to test how this algorithm fares in the real world where the quality of images may vary from clinic to clinic, says Aaron Lee, an ophthalmologist at the University of Washington in Seattle. But this kind of AI could be especially useful in rural and developing regions where medical resources and specialists are scarce and people otherwise wouldn’t have easy access to in-person eye exams.

AI might also be able to use eye pictures to identify other kinds of health problems. One algorithm that studied retinal images from over 284,000 patients could predict cardiovascular health risk factors such as high blood pressure.

The algorithm was 71 percent accurate in distinguishing eye images between smoking and nonsmoking patients, according to a report February 19 in Nature Biomedical Engineering. And it predicted which patients would have a major cardiovascular event, such as a heart attack, within the next five years 70 percent of the time.

With AI getting more adept at screening for a growing list of conditions, “some people might be concerned that this is machines taking over” health care, says Caroline Baumal, an ophthalmologist at Tufts University in Boston. But diagnostic AI can’t replace the human touch. “Doctors will still need to be there to see patients and treat patients and talk to patients,” Baumal says. AI will just help people who need treatment get it faster.